Yes, you can, but you cannot trigger more than one autoresponder on submission. You can, however, trigger a different autoresponder each time a certain condition is met on the form with the help of autoresponder rules. For example, if Field A contains a value Y, then the submitter will receive a particular autoresponder.
Go to Settings → Rules → Autoresponder Rules to set conditions and associate them the confirmation message/autoresponder you want.
Autoresponders are created in the Settings → Notifications section of you form, under Form User Options.